Francois Bertelli Selected Research

pyrrolo(2,1-c)(1,4)benzodiazepine

1/2022	Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
10/2018	Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.

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Francois Bertelli Research Topics

Disease

3	Neoplasms (Cancer) 01/2022 - 10/2018
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 10/2018
1	African Trypanosomiasis (Nagana) 04/2011
1	Infections 09/2004

Drug/Important Bio-Agent (IBA)

3	Immunoconjugates (Immunoconjugate)IBA 01/2022 - 10/2018
2	pyrrolo(2,1-c)(1,4)benzodiazepineIBA 01/2022 - 10/2018
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 10/2018
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2022
1	auristatinIBA 01/2022
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022
1	monomethyl auristatin EIBA 01/2022
1	olaparibIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2020
1	MEDI3726IBA 10/2018
1	glutamate carboxypeptidaseIBA 10/2018
1	AntigensIBA 10/2018
1	Histones (Histone)IBA 10/2018
1	Proteins (Proteins, Gene)FDA Link 04/2011
1	Glycogen Synthase KinasesIBA 04/2011
1	SolutionsIBA 09/2004

Therapy/Procedure

1	Immunotherapy 01/2020
1	Castration 10/2018